Cell and Molecular Genetics Training Program Fellows

Jon Almaden
Jonathan Almaden
Biological Sciences
Advisor: Alex Hoffman

 

The role of NFkB transcriptional regulators in various aspects of B-cell differentiation, maintenance and antigen response.

Ann Atwood
Ann Atwood
Biological Sciences
Advisor: Steve Kay

Investigating how the mammalian circadian clock controls and integrates anabolism and catabolism throughout the diurnal cycle.

Russ Dekelver
Russ DeKelver
Biological Sciences
Advisor: Dong-Er Zhang

The action of a repressor complex in the control of genes responsible for leukemia.

Tiffany Dunbar
Tiffany Dunbar
Biological Sciences
Advisor: Emily Troemel

Studying effects of pseudomonas on C. elegans stress pathways by direct analysis and execution of an RNAi screen for factors important in pathogenesis.

Daniel Egan
Daniel Egan
Biological Sciences
Advisor: Reuben Shaw

 

Studying the interface between the autophagic pathway and the AMPK metabolic regulator.

Marcy Erb
Marcy Erb
Biological Sciences
Advisor: Joe Pogliano

 

Studying large phage in a non-model bacterium to understand universal mechanisms of DNA transfer and infection.

Anthony Farina
Chemistry & Biochemistry
Advisor: Teru Nakagawa

Working on several projects involving single particle electron diffraction, on NMDA receptors and Ephrins. Just found out X-ray structure for receptor this week.

Britt Flaherty

Britt Flaherty
Biological Sciences
Advisor: James Golden

Studying the mechanisms of heterocyst formation in cyanobacterium anabaena, one of the simplest organisms to employ terminal differentiation.

Paul Gasper
Chemistry & Biochemistry
Advisor: Andrew McCammon

Using molecular simulations to understand the interactions and function of thrombin and thrombomodulin, that control the clotting and anti clotting functions of thrombin.

Jon Goodwin
Jon Goodwin
Biological Sciences
Advisor: Reuben Shaw

 

Investigating the role of LKB kinases and other stimuli in the control of the master metabolic regulator AMP-dependent kinase (AMPK).

Dana Gwinn
Dana Gwinn
Biological Sciences
Advisor: Reuben Shaw

 

Studying phosphorylation in the cell cycle regulation of raptor, a TOR kinase.

Tammy Haselkorn
Tammy Haselkorn
Biological Sciences
Advisor: Theresa Markow

 

Investigating the biology and natural history of the widely distributed Gram-positive endosymbiont Spiroplasma of Drosophila.

Meghan Hogan
Meghan Hogan
Biological Sciences
Advisor: Marc Montminy

 

Exploring the role and involvement of adipose-expressed TORC3 to test its role in metabolic syndrome and obesity.

Derek Joyce
Derek Joyce
Biological Sciences
Advisor: Andrew Dillin

Investigating the role of proteasome activity on the aging response, and age-related alterations in proteasome function.

Albert Kim
Albert Kim
Biological Sciences
Advisor: David Traver

 

Investigating the differentiation and formation of vertebrate red blood cells in zebrafish.

Anne Lamsa
Anne Lamsa
Biological Sciences
Advisor: Kit Pogliano

 

Studying regulation of YidC and SpoIIIJ,  proteins involved in membrane protein insertion, in B. Subtilis.

Joseph Lucas
Joseph Lucas
Biological Sciences
Advisor: Cornelis Murre

Studying the mechanism of structure-based regulation of Id locus regulation; developing new visualization techniques involving creation of selectively binding Zn finger proteins.

Matt Lundberg
Matt Lundberg
Biological Sciences
Advisor: Senyon Choe

Studying the functions and action of the Mistic family of membrane-associated proteins in Bacillus, to understand the basic functions of this class, and as a strategy of increasing membrane protein expression.

Anne Medina-Morales
Chemistry & Biochemistry
Advisor: Faik Texcan

Exploring methods to reengineer proteins to acquire novel functions, with emphasis on imparting selective Cu1+  binding for use in basic and biotechnological contexts.

Maria Mihaylova
Maria Mihaylova
Biological Sciences
Advisor: Reuben Shaw

 

Exploring the role of histone deacetylases (HDACs) in AMPK dependent regulation of metabolism.

Michaelanne Munoz
Michaelanne Munoz
Biological Sciences
Advisor: Paul Slesinger

Analyzing the actions and mechanism of a selective protein regulator of ion channels, using electrophysiology and gene disruptions.

Anil Naramsimha
Anil Narasimha
Biological Sciences
Advisor: Steven Dowdy

Studying the multifaceted regulation of Rb cell cycle regulator protein by phosphorylation.

Boris Reznik
Boris Reznik
Biological Sciences
Advisor: Jens Lykke-Andersen

Studying the function of 3’A-rich repeats in mRNA stability and expression.

Govind Shah
Govind Shah
Biological Sciences
Advisor: Clodagh O'Shea

Studying the role and mechanism of p53 inactivation in the adenovirus life cycle.

Helena Sun
Helena Sun
Biological Sciences
Advisor: Joseph Noel

 

Eric Sun
Eric Sun
Biological Sciences
Advisor: Milton Saier

Employing a combination of bioinformatic and bench approaches to understand the mechanisms of selective and energy-dependent membrane transporters.

Tom Suter
Tom Suter
Biological Sciences
Advisor: Geoff Rosenfeld

Exploring the role of active genome demethylation in the function of hormone receptors.

Roberto Tinoco
Roberto Tinoco
Biological Sciences
Advisor: Elina Zuniga

Studying the role of TGF-b signaling in the action of antiviral T cells, with the hope of employing this connection to develop new antiviral therapies.

Sharon Torigoe
Sharon Torigoe
Biological Sciences
Advisor: Jim Kadonaga

Investigating the hypothesis that HMGB proteins function by antagonism of histone H1 at the level of the nucleosome.

Nicholas Treuheit
Chemistry & Biochemistry
Advisor: Betsy Komives

Studying the biochemical and structural features of the regulation of thrombin activity by thrombomodulin, with an emphasis on the in-solution analysis of this control axis.

Sam Ulin
Sam Ulin
Biological Sciences
Advisor: Lei Wang

Using non-canonical amino acid technology to investigate the function and ligands of an orphan nuclear receptor implicated in dopaminergic neuron differentiation.

Jesse Vargas
Jesse Vargas
Biological Sciences
Advisor: Martin Hetzer

Studying the role of lamins in the control of nuclear dynamics and integrity.

Anita Zarska
Biological Sciences
Advisor: Rick Firtel

Using biochemical and genetic approaches to understand the role of GAPs in eukaryotic chemotaxis, using Dictyostelium.